Building Design And Construction Vicente 156l PATCHED
One of the most important objectives of this research field is the improvement of the process of bladder tissue building, obtaining an impermeable epithelial surface to obtain well-differentiated UCs and SMCs and a suitable mechanically resilient and compliant ECM. Therefore, the first step usually consists in developing a urinary bladder bioreactor with an efficient process monitoring that recapitulates the in vivo bladder function in a reliable and reproducible way. Bioreactor design criteria must include the possibility of mechanical and nutrient environments control to promote cell proliferation, differentiation, and favorable matrix deposition [41].
Building Design And Construction Vicente 156l